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Publication in J Cachexia Sarcopenia Muscle

Altered hepatic AHR signaling in cancer cachexia impacts liver metabolism  

Laure Bindels and her team showed that altered hepatic AHR receptor signalling could promote liver disorders in cancer cachexia, a syndrome that induces weight loss, muscle wasting and immune deficiency.

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Publication in Microbiome

Influence of the gut microbiota on eating behaviour  

Amandine Everard's team demonstrated a causal link between the intestinal microbiota, and more precisely a phenolic metabolite produced by it, and compulsive eating behaviours.

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Publication in J Control Release

Oral formulation with lipid nanoparticles : an alternative to injections?  

Ana Beloqui and her team developed an oral formulation, based on lipid nanoparticles, of drugs usually administered by subcutaneous injection in the treatment of non-alcoholic fatty liver disease.

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Publication in Nature

RHOJ : contrôle de la résistance à la chimiothérapie  

Cédric Blanpain's team discovered that RHOJ allows cancer cells with EMT to resist chemotherapy.

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Publication in Nature Immunology

Capacité de prolifération inattendue des monocytes sanguins  

Thomas Marichal and his team have discovered that blood monocytes, previously considered to be differentiated cells, are in fact capable of proliferating to replace tissue macrophages.

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Publication in Cell

CnoX: an unexpected partner for GroEL  

Jean-François Collet and colleagues discovered that the chaperone GroEL works with CnoX, a chaperedoxin that controls the redox quality of GroEL substrates.

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2023 George Eisenbarth Memorial Lecture award  

Decio L. Eizirik is the recipient of the prestigious George Eisenbarth Memorial Lecture that will be delivered at the 15th annual Network for Pancreatic Organ Donors with Diabetes (nPOD) meeting in Florida, USA.

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ISSCR Momentum Award  

Cédric Blanpain is the winner of the Momentum Award 2023 of the International Society for Stem Cell Research (ISSCR). This is the first time that such a prestigious award has been given to a researcher based in Europe.

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2023 Earl P. Benditt Award  

Miikka Vikkula is the recipient of the prestigious Earl P. Benditt Award which he will receive at the 2023 edition of the North American Vascular Biology Organization (NAVBO) meeting in Rhode Island, USA.

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Publication in Nucleic Acids Research

« Z » for Zalpha  

Alain Vanderplasschen and his team demonstrated a key role for the Zalpha protein domain of Cyprinid herpesvirus 3 in the mechanism of viral infection in carp.  

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Publication in Blood

GARP in cancer: the story continues…  

Sophie Lucas’ team showed that the strategy of blocking GARP, a novel immuno-oncology target under clinical investigation for solid cancers, also has potential in "liquid" tumours.

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