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Spin-off creation

NeuVasQ: An innovative approach to fight against neurovascular and neurodegenerative diseases  

From disruptive research of scientific founder Benoit Vanhollebeke (WELBIO - ULB) to the development of blood-brain barrier pharmaceuticals aiming at repairing neurovascular function and neurodegenerative diseases.

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Publication in Gut

D. welbionis : potential implications for metabolic diseases  

A new bacterium, made in Belgium

Patrice Cani (WELBIO - UCLouvain) describes the properties displayed by D. welbionis, a new bacterium present in 70% of the population, that open the doors for potential treatment for type 2 diabetes, obesity and inflammatory diseases.

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Publication in Nature Communications

Wobble transfer RNA modifications optimize dynamic proteome expression  

Pierre Close (WELBIO – ULiège) and Francesca Rapino describe how the regulation of transfer RNAs and modification of their anticodon impact the dynamics of protein synthesis and regulate protein folding and stability.

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Publication dans Science Advances

Maladies auto-immunes, des signatures moléculaire similaires au niveau des tissus cibles ?  

L'utilisation d'inhibiteurs de TYK2 - déjà utilisés pour d'autres maladies auto-immunes - protège les cellules β contre les dommages induits par le système immunitaire

Decio Eizirik (WELBIO - ULB) et son équipe décrivent des signatures moléculaires similaires entre différentes maladies auto-immunes, identifiant des voies clés qui pourraient être ciblées pour la thérapie.

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Publication in Nature

Cancer: Tumor driver promoting EMT, metastasis and resistance to therapy  

New therapy for FAT1 mutated cancers

Cédric Blanpain (WELBIO – ULB) and his team identify the functions of FAT1, one of the most frequently mutated cancer gene drivers, uncovering that FAT1 mutations promote invasive features, metastasis and resistance to commonly used anti-cancer drugs

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The "Belgian Nobel Prize"

The Francqui-Collen Prize 2020 is awarded to Cédric Blanpain  

Prize awarded to a Belgian investigator less than 50 y.o. “who has made an important contribution to science augmenting the prestige of Belgium".”

Director of the Laboratory of Stem Cells and Cancer (ULB), WELBIO investigator, Pr. Cédric Blanpain is awarded the Francqui-Collen Prize for his fundamental research in cancer and stem cells biology.

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Important collaboration agreement with Kaneka Eurogentec

From fundamental research on bacterial stress to the production of biomedicines.  

The use of biomedicines is disrupting current medicine

Kaneka and its Walloon subsidiary, Kaneka Eurogentec S.A., enter into a partnership with Jean-François Collet's laboratory (WELBIO - UCLouvain) by funding a new joint research group at the Duve Institute.

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Déclarez-vous volontaire !

Luttons tous ensemble contre le Covid-19  

Boostons la recherche clinique

WELBIO lance aujourd’hui une plateforme digitale permettant aux citoyens de se déclarer volontaires pour des études cliniques relatives au Covid-19 : https://rechercheclinique.be/

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Publication in Science Translational Medicine

A new target and a potential cure of cardiac hypertrophy inspired from plant biology  

Blockade of transmembrane transport of hydrogen peroxide by cardiac Aquaporin-1 with Brahmi prevents myocardial remodelling

These results from the team of Jean-Luc Balligand (WELBIO –  UCLouvain) pave the way for the development of more potent molecules to block aquaporin and treat heart failure more efficiently.

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Publication in Gut

Targeting our second brain to fight diabetes  

A ‘jammer’ blocks communication between the gut and the brain

This jammer prevents proper regulation of sugar, causing insulin resistance in people with diabetes. Patrice Cani (WELBIO - UCLouvain) and Claude Knauf (INSERM) also discover that a lipid produced by our body helps preventing this dysfunction.

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Publication in Nature Communications

The RNA alphabet is written letter after letter  

A new step towards understanding the complex RNA alphabet

François Fuks (WELBIO – ULB) and his colleagues show the key role of a chemically modified RNA letter, hydroxymethylcytosine (hmC), during the differentiation of embryonic stem cells.

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Publication in Nature Communications

A novel immunotherapy to fight cancer  

Combining two complementary immunotherapies increases the efficacy of treatments against cancer

Sophie Lucas (WELBIO – UCLouvain) and her team neutralize a molecule that blocks immune responses against cancer. This novel form of immunotherapy induces tumor regressions by strongly increasing the efficacy of another well-known immunotherapy.

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